Nbpf domain search

NBPF1 - Wikipedia

★ ★ ★ ☆ ☆

We are jointly proposing a new name for a protein domain of approximately 65 amino acids that has been previously termed NBPF or DUF1220. Our two labs independently reported the initial studies of this domain, which is encoded almost entirely within a single gene family. The name Neuroblastoma Breakpoint Family (NBPF) was applied to this gene family when the first identified member of the ...

NBPF1 - Wikipedia

A proposal to change the name of the NBPF/DUF1220 domain ...

★ ★ ★ ☆ ☆

These findings lend support to the view that DUF1220 domain dosage is a key factor in the determination of primate (and human) brain size. Here we analyze 41 animal genomes and present the most complete account to date of the evolutionary history and genome organization of DUF1220 domains and the gene family that encodes them (NBPF).

A proposal to change the name of the NBPF/DUF1220 domain ...

Evolutionary History and Genome Organization of DUF1220 ...

★ ★ ★ ☆ ☆

DUF1220 is a protein domain that shows a striking human lineage-specific (HLS) increase in copy number and may be involved in human brain evolution. The protein domain has also been linked to several neurogenetic disorders such as schizophrenia and increased severity of autism. In 2018, the name of the DUF1220 domain was changed to the Olduvai domain based on data obtained since initial ...

Evolutionary History and Genome Organization of DUF1220 ...

DUF1220 - Wikipedia

★ ★ ★ ★ ★

8/3/2005 · In NBPF1, several pairs of exon types encode a novel protein domain, which we call an NBPF repeat. This domain is partly covered by the protein family database (PFAM) domain of unknown function, DUF1220 (accession number PF06758).

DUF1220 - Wikipedia

Novel Gene Family NBPF: Intricate Structure Generated by ...

★ ★ ☆ ☆ ☆

To identify the genes bound by NF-κB in TNFα-stimulated HeLa cells, we recently performed ChIP-Seq assays and found that many genes were bound by this transcription factor (Xing et al., 2013).Among these genes, the genes of NBPF family attracted our attention because they were covered by many ChIP-Seq peaks of high confidence (with enrichment fold over 20) (Table 1; Figs. S2 and S3).

Novel Gene Family NBPF: Intricate Structure Generated by ...

NBPF is a potential DNA-binding transcription factor that ...

★ ★ ★ ★ ☆

9/1/2012 · These findings lend support to the view that DUF1220 domain dosage is a key factor in the determination of primate (and human) brain size. Here we analyze 41 animal genomes and present the most complete account to date of the evolutionary history and genome organization of DUF1220 domains and the gene family that encodes them ( NBPF ).

NBPF is a potential DNA-binding transcription factor that ...

Evolutionary History and Genome Organization of DUF1220 ...

★ ★ ★ ★ ★

8/14/2017 · DUF1220 protein domains found primarily in Neuroblastoma BreakPoint Family (NBPF) genes show the greatest human lineage-specific increase in copy number of any coding region in the genome. There are 302 haploid copies of DUF1220 in hg38 (~160 of which are human-specific) and the majority of these can be divided into 6 different subtypes (referred to as clades).

Evolutionary History and Genome Organization of DUF1220 ...

High resolution measurement of DUF1220 domain copy number ...

★ ★ ☆ ☆ ☆

Search. nbpf.nl Offici?le website Nederlandse Bodybuilding & Physique Sports ... Offici?le website Nederlandse Bodybuilding & Physique Sports Foundation. nbpf.nl is ranked 0 in the world (amongst the 40 million domains). A low-numbered rank means that this website gets lots of visitors. ... Website / Domain: nbpf.nl: Website IP Address: 193.242 ...

High resolution measurement of DUF1220 domain copy number ...

nbpf.nl Offici?le website Nederlandse Bodybuilding ...

★ ★ ★ ★ ★

the evolutionary history and genome organization of DUF1220 domains and the gene family that encodes them (NBPF). Included among the novel features identified by this analysis is a DUF1220 domain ...

nbpf.nl Offici?le website Nederlandse Bodybuilding ...

Evolutionary History and Genome Organization of DUF1220 ...

★ ★ ★ ★ ★

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Evolutionary History and Genome Organization of DUF1220 ...

NBPF - Homo sapiens (Human) - uniprot.org

★ ★ ☆ ☆ ☆

1-303-893-0552. Speak with a domain specialist. 9am - 5pm MST

NBPF - Homo sapiens (Human) - uniprot.org

HugeDomains.com - Browse Domains by Category

★ ★ ★ ★ ★

9/7/2012 · In order to detect CNVs in DUF1220-domain-encoding sequences in the 1q21.1-1q21.2 region of the genome among individuals, we designed high-density custom human microarrays by using Agilent Technologies 8x60K platform. The array was enriched for both unique and nonunique 60 mer probe sequences that ...

HugeDomains.com - Browse Domains by Category

DUF1220-Domain Copy Number Implicated in Human Brain-Size ...

★ ★ ★ ★ ☆

The NBPF gene family. ... The search for NBPF-interacting prot e i n s r e v e a l e d t w o h i t s s o f a r: ... that the coiled-coil region in the N-terminal domain of NBPF interacts with the ...

DUF1220-Domain Copy Number Implicated in Human Brain-Size ...

(PDF) The NBPF gene family - ResearchGate

★ ★ ★ ★ ☆

4/3/2019 · Domain Name Valuations. Understanding valuations is important when buying an aftermarket domain name. If you are reading this you most likely have been doing research into domain name valuations. Beware of free appraisal services, because they are inconsistent, oftentimes arbitrary, and potentially misleading. ...

(PDF) The NBPF gene family - ResearchGate

HugeDomains.com - Domain Name Valuations

★ ★ ★ ★ ★

5/20/2014 · The DUF1220-encoding NBPF genes required the most corrections, with 3 genes removed, 2 genes reassigned to the 1p11.2 region, 8 genes requiring assembly corrections for DUF1220 domains (~91 DUF1220 domains were misassigned), and multiple instances of nucleotide changes that reassigned the domain to a different DUF1220 subtype.

HugeDomains.com - Domain Name Valuations

Finished sequence and assembly of the DUF1220-rich 1q21 ...

★ ★ ☆ ☆ ☆

« hide 10 20 30 40 50 mfrlsrelld ekgpevlqds ldrcystpsg cleltdscqp yrsafyvleq 60 70 80 90 100 qriglavdmd eiekyqevee dqdpscprls relldekepe vlqdsldrcy 110 120 130 140 150 stpsgylelp dlgqpyssav ysleeqylgl aldvdrtkkd qeeeedqgpp 160 170 180 190 200 cprlsrelle vvepevlqds ldrcystpss cleqpdscqp ygssfyalee 210 220 230 240 250 khvgfsldvg eiekkgkgkk rrgrrskker rrgrkegeed qnppcprlsr 260 270 280 290 300 ...

Finished sequence and assembly of the DUF1220-rich 1q21 ...

NBPF20 - Neuroblastoma breakpoint family member 20 - Homo ...

★ ★ ☆ ☆ ☆

6/25/2015 · The expansion of DUF1220 domain copy number during human evolution is a dramatic example of rapid and repeated domain duplication. Although patterns of expression, homology, and disease associations suggest a role in cortical development, this hypothesis has not been robustly tested using phylogenetic methods.

NBPF20 - Neuroblastoma breakpoint family member 20 - Homo ...

Phylogenetic Analysis Supports a Link between DUF1220 ...

★ ★ ★ ★ ☆

9/7/2012 · Excluding the ancestral DUF1220 domain, the remaining DUF1220-domain-encoding DNA sequences can be divided into six subgroups, or clades, designated HLS1, HLS2, HLS3, CON1, CON2, and CON3. 5 The copy number of DUF1220 sequences that belong to HLS clades has increased markedly in the human lineage, whereas the copy number of DUF1220 sequences ...

Phylogenetic Analysis Supports a Link between DUF1220 ...

DUF1220-Domain Copy Number Implicated in Human Brain-Size ...

★ ★ ☆ ☆ ☆

PDE4DIP, NBPF, and DUF1220 domain chromo- high enough to be formally classified by BLAT/BLAST as containing somal positions in human, orangutan, macaque, marmoset, cow, dog, a DUF1220 domain until the emergence of the mammalian lineages. horse, and pig were determined using the UCSC genome browser.

DUF1220-Domain Copy Number Implicated in Human Brain-Size ...

Evolutionary history and genome organization of DUF1220 ...

★ ★ ☆ ☆ ☆

[NBPF]) was independently identified when one of its members was found to be disrupted by a rearrangement in an individual with neuroblastoma (MIM 613017).3 Analysis of DUF1220 sequences indicated that the domain shows an exceptional HLS copy-number expansion that decreases generally with evolutionary distance from hu-

Evolutionary history and genome organization of DUF1220 ...

DUF1220-Domain Copy Number Implicated in Human Brain-Size ...

★ ★ ★ ☆ ☆

Search. find publications by category + ... NBPF was also identified as a nuclear protein by in silico prediction and immunolocalization. Finally, the bioinformatics analysis revealed that most of NBPF proteins contained classical nuclear localization signals (NLSs) and a conserved DNA-binding domain similar to the transcription factor stat3b ...

DUF1220-Domain Copy Number Implicated in Human Brain-Size ...

NBPF is a potential DNA-binding transcription factor that ...

★ ★ ★ ★ ☆

The 65-amino acid DUF1220 domain appears within numerous proteins (Popesco et al., 2006). Sequences encoding these domains are virtually all primate-specific, show signs of positive selection, and are increasingly amplified generally as a function of a species' evolutionary proximity to humans, where the greatest number of copies (212) is found.

NBPF is a potential DNA-binding transcription factor that ...

OMIM Entry - * 610414 - NEUROBLASTOMA BREAKPOINT FAMILY ...

★ ★ ★ ☆ ☆

1/11/2016 · Protein ubiquitination catalyzed by E3 ubiquitin ligases play important modulatory roles in various biological processes. With the emergence of high-throughput mass spectrometry technology, the proteomics research community embraced the development of numerous experimental methods for the determination of ubiquitination sites. The result is an accumulation of ubiquitinome data, coupled with …

OMIM Entry - * 610414 - NEUROBLASTOMA BREAKPOINT FAMILY ...

A new scheme to discover functional associations and ...

★ ★ ★ ★ ★

Roberts, T; Chernova, O; et al. NB4S, a member of the TBC1 domain family of genes, is truncated as a result of a constitutional t(1;10)(p22;q21) chromosome translocation in a patient with stage 4S neuroblastoma. HUMAN MOLECULAR GENETICS 7:1169-1178(1998).

A new scheme to discover functional associations and ...

NBPF7 - Creative BioMart

★ ★ ★ ★ ★

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

NBPF7 - Creative BioMart
Gutworm-lyrics-search.html,Gw-faq-errata.html,Gwerkova-lyrics-search.html,Gwsports-video-search.html,Gxtechnical-search-yahoo.html